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Considering again that the myogenic stem cell activator HGF is found in an ECM-bound state 19,20,21,22,26 and undergoes nitration of tyrosine residues (Y198 and Y250) with aging 32,32,62 and muscle disuse (Kuwakdo et al., 2025), the present in vivo experiments provide a robust platform showing the potential for LASSS that could efficiently reduce or delay the nitration-dysfunction of ECM-bound HGF under peroxynitrite-generating conditions

In this form, the vitamin is particularly well tolerated and also suitable for people with a sensitive stomach

It serves as a high-purity analytical reagent used in protein purification processesspecifically in the GST-tagging system

American Academy of Dermatology meeting, February 2002

Curr Pharm Des