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Medical guidelines state the drug is unlikely to work long-term if you haven't lost 3% to 5% of your starting weight after 12 weeks on a full dose

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Lancet 2016;387:67990

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Diabetes 60:391397 Qureshi SA, Rios Candelore M, Xie D et al (2004) A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects