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Flow cytometry-based examination of the ferrous iron levels in 5-FU-derived persister tumors revealed increased ferrous iron staining in these residual tumors ( Figure 5D )

Quantitative proteomics identified 3 oxidative phosphorylation genes with clinical prognostic significance in gastric cancer

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That extended window means it can drive sustained muscle protein synthesis, satellite cell activation, and nutrient partitioning in a way that short-acting IGF-1 simply can't

It is synthesized in keratinocytes and is highly upregulated in psoriatic skin [94] and epithelial skin tumors [95]