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Obesity and visceral adiposity are key drivers of HFpEF development and progression, and this may be even more amplified in women, who represent the majority of people with the disease, and bear a heavier burden of symptoms and physical limitations due to HFpEF, says Mikhail Kosiborod, MD, FACC, senior author of the study and a cardiologist at Saint Lukes Mid-America Heart Institute

Then, gradually, they start to return to the way they felt before

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Until recently, clinicians mainly relied on lifestyle interventions and insulin titration