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Genome Biology, 2(5): 14

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These findings demonstrate that both basal and agonist-induced GLP-1R phosphorylation are critical for receptor signalling in -cells, revealing a previously unappreciated role for basal phosphorylation in shaping receptor behaviour and establishing a positive link between GLP-1R phosphorylation and -cell signalling competence

Figure 4 4.4.4.1 Convergent nephrotoxic mechanisms Despite originating from disparate amino acid precursors, protein-bound uremic toxins (IS, pCS, PAGln) share common renal injury mechanisms