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Most often, the vial is sealed with a self-healing stopper whose elastic-like material closes over any punctures made in it

The exact treatment plan will be determined on an individual basis

To minimize side effects (lung toxicity, ototoxicity, nephrotoxicity) some pediatric protocols used reduced dose of bleomycin from once per week to once per cycle (PEb) [322,323,324] or carboplatin instead of cisplatin [325, 326]

Switched to pills because he was fighting the shots

The typical protocol here is on the higher end 500 mcg twice daily starting as soon as possible post-op and continuing for 68 weeks