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Longitudinal studies (Khavinson et al.) in rodents have demonstrated that Epithalon can increase maximum lifespan by 11-25%

In the gastrointestinal tract, current studies have identified that metformin effects glucose uptake and absorption, influences GLP-1 secretion, modulates immune homeostasis, and regulates the gut microbiota, detailed information was drawn in Figure 1

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Zareba P, Colaci DS, Afeiche M, et al

The clinical manifestations include ovulatory disorders, irregular menstruation, hyperandrogenemia, and polycystic ovarian morphology [2]

1 2 Rosen's Emergency Medicine Concepts and Clinical Practice