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In order to be successfully synthesized in ER, the chaperone GRP78 is induced and activated to promote the refolding process of misfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

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These results indicate that the CKAAKN peptide promotes specific binding of ORI@CPD-Lipo to CKAAKN-positive BxPC-3 cells and facilitates cellular internalization via a Wnt protein-mediated pathway (Fig