FIGURE 6 Activation of Adaptive Stress Responses by AQ-QI and DEAQ-QI and Effects of GSTP1 The stress responses induced by AQ-QI and DEAQ-QI exposure were measured with a high-content image-based BAC-GFP stress responses reporter assay for oxidative stress, ER stress, DNA damage stress and inflammatory stress (Wink et al., 2014, 2017)
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4 , e001993 (2015)
[4] The proposed mechanism of action, based only on preclinical animal studies, involves potential modulation of growth factor pathways, particularly vascular endothelial growth factor (VEGF), which may promote angiogenesisthe formation of new blood vessels
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Micro-CT scanning images were acquired on Skyscan1176 (Bruker)
