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Patients considering GLP-1 receptor agonist or dual GIP/GLP-1 therapy should understand that these medications facilitate weight loss through appetite reduction and decreased food intake, not by "speeding up metabolism" or burning additional calories at rest

European Medicines Agency (EMA) Eli Lilly typically files for European approval (through the EMA's centralized procedure) around the same time as the FDA submission, sometimes within a few months

However, diabetes (49% vs 14%) and hypertension (57% vs 38%) were more common in the treatment group

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Food and Drug Administration (FDA) for use by the general public