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The split between weightloss and diabetes indications meant carriers and sponsors will need clear criteria on whether to restrict coverage to diabetes (and, if so, under what clinical rules), or to extend support to obesity and cardiometabolic risk reduction more broadly

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TLR9 is functionally expressed in microglia and astrocytes, which serve as the brains primary immune effector and supporting glial cells, respectively [129]

8 Conclusions and future perspective Polyphenols, a diverse class of natural compounds, exhibit a wide range of biological activities largely determined by the number and position of their hydroxyl groups

The role of homocysteine-lowering B-vitamins in the primary prevention of cardiovascular disease

B., Ali, A., Martnez, J