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Critically, the GSH/GSSG redox couple maintains the thiol groups of structural and enzymatic proteins in their reduced, functional state preventing irreversible oxidative cross-linking that would impair protein function
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Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase
On the other hand, the treatment policity estimand was used to evaluate the treatment effect for all randomized participants regardless of whether the trial was discontinued early or rescue medicien was used [2]