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Source: Evaluate Pharma, World Obesity Federation, Putnam Analysis Q2, 2025 Unmet Needs and Potential Differentiation Levers Despite extraordinary promise, there are still unmet needs that biopharma companies can target to address: GI Tolerability The most common GI adverse events (nausea, vomiting, and diarrhea) often lead to therapy discontinuation

Red blood cell parameters: Red blood cell count (RBC), hemoglobin (Hb), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW-SD, RDW-CV)

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Liraglutide is extensively bound to plasma protein (greater than 98%)

By following proper injection techniques, rotating sites, and maintaining consistency, you'll maximize the benefits of your treatment while minimizing side effects

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