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People often assume a sprain will heal on its own, returning to activity before tissues have properly remodeled

Oral B12 supplementation: High-dose oral cyanocobalamin (10002000 micrograms daily) represents an alternative for patients with dietary deficiency or those without severe deficiency or neurological symptoms, and for those unable or unwilling to receive injections

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doi:10.1111/dom.15184 Pratt E, Ma X, Liu R, et al

Acknowledgements We gratefully acknowledge the work of past and present members of our laboratory.

The positron emission tomography (PET) was used to examine brain oxygen consumption and cerebral blood flow and revealed that patients with overt hepatic encephalopathy and those with liver cirrhosis without overt hepatic encephalopathy had a lower cerebral metabolic rate of oxygen and cerebral blood flow than healthy subjects 4