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These medications are expensive due to high research costs, complex manufacturing processes, patent protection, and rising demand with limited supply
After permeabilization, antigens were retrieved by heating the sections in an autoclave for 1 h at 70 C with a Histo VT one (Nakalai Teaque, Kyoto, Japan)
Its half maximal inhibitory concentration (IC50) for GIPR is 42.4 nM, and its EC50 for GLP-1R is 24.4 pM in a human cell-based functional assays (74)
[Contains Engs lizard only its mother could love quote] Molteni M
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Both are built on a GIP-based peptide scaffold
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