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Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: the SCALE maintenance randomized study

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The limited data that has been published has shown that the ASA Practice Guidelines for Preoperative Fasting used in most medical institutions does not adequately protect patients who may have delayed gastric emptying secondary to GLP-1-RA use

So, GLP-1s lead to clinically significant weight loss rarely observed in intervention trials that use lifestyle interventions without medications

This weight loss was probably caused by a decrease in energy intake but the researchers also discovered a number of additional processes that may have helped, such as a decrease in hunger and food cravings, improved behavior control for eating, and a decreased relative preference for fatty, energy-dense foods

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