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George Kamel explains that as people lose weight, they also lose the underlying fat that helps plump and fill out the face, giving them a sunken look, and experience a decline in collagen and elastin

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Topline results from the SURMOUNT-OSA trials showed tirzepatide may have benefit beyond body weight reductions, as participants receiving the agent had greater reductions in apnea-hypopnea index (AHI) than placebo

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Clinicians who have been focused on obesity alone are going to need to reckon with the psychiatric and addiction applications of GLP-1 receptor agonists over the next three years

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