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It is essential to continue with prescribed treatments and lifestyle modifications whilst viewing any supplementation as potentially complementary rather than alternative to proven interventions

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Lifestyle Factors: Because cigarette smoking and excessive alcohol intake cause an increase in free radical production, both habits deplete glutathione levels

Limited data from small clinical trials have shown marginal improvement in neuropathic pain with a number of over-the counter-supplements, including acetyl-l-carnitine and alpha lipoic acid (Table 4)

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