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Additionally, we discovered that a GSH threshold of 10.2 nmol/mg effectively differentiates resistant cells from sensitive cells, with an AUC of 0.913, providing a robust distinction between chemotherapy-resistant and sensitive patients

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After that, different transferrin receptor ligands have been investigated for nanoparticle brain-targeting drug delivery systems

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The importance of mGSH is mainly based on its detoxification of hydrogen peroxide, mitochondrial lipid membrane peroxidation, or xenobiotics under the catalysis of enzymes such as GPX or GST [58]