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Pharmaceutics 17 (1), 90

There are great variations in nuclear GSH concentration and its regulation mechanisms during the cell cycle since cells starting the proliferation phase have high levels of nuclear GSH, while resting cells have similar or lower GSH levels in the nucleus than in the cytoplasm (68, 72, 73)

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Future research should aim to replicate this study with a well-characterized population of ASD subjects to further assess glutathiones key role as a master antioxidant in treating the redox imbalance observed in ASD

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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Pierce GB, Parchment RE, Lewellyn AL