It activates the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor, pathways involved in appetite regulation, satiety, glucose control, and weight management
Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management
For women with PCOS, this triple-action approach holds particular promise
Endocrinology 156 , 847857 (2014)
10.3390/ijms19092505 25 CorreiaS
For those who have struggled with plateaus on existing medications, or who face multiple interconnected health issues, this kind of therapy may offer a more complete solution