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Others require emergency intervention if vomiting is uncontrollable, blood sugar drops below 54 mg/dL, or signs of dehydration (extreme thirst, dry mouth, decreased urination) persist

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Semaglutide for the treatment of cognitive dysfunction in major depressive disorder: A randomized clinical trial

And research suggests heavy drinking is more consistently linked to weight gain than light or moderate intake

Ablation of myt-1 significantly reduced the longevity of eat-2(ad1116) mutants, suggesting that it was partially indispensable for life span extension due to dietary restriction (Figure 8B and Supplemental Figure 6A), but with a smaller effect size compared with its effect on WT worms, as confirmed by Cox proportional hazards (CPH) analysis ( P = 0.00004)

Dry mouth is a recognized but relatively rare side effect of semaglutide