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In the pancreas, these agents enhance glucose-dependent insulin secretion while suppressing inappropriate glucagon release, improving glycemic control with a low risk of hypoglycemia when used alone (though this risk increases when combined with insulin or sulfonylureas)

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Physiol Rev 85(4):13031342

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The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice

Improvement of seminal quality and sexual function of men with oligoasthenoteratozoospermia syndrome following supplementation with L-arginine and Pycnogenol(R)