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Collectively, these mitochondrial dysfunction-associated events contribute to ferroptosis-related nucleus pulposus cell injury and extracellular matrix degradation in IDD, thereby suggesting that targeting mitochondrial dysfunction may represent a potential therapeutic strategy for IDD

Nelfinavir, an HIV protease inhibitor, induces apoptosis and cell cycle arrest in human cervical cancer cells via the ROS-dependent mitochondrial pathway

The clinical evidence is clearest for two approaches: liposomal delivery (faster blood level increases, shown in the Sinha et al

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This often appears alongside iron deficiency in Indian women, as both tend to be low at the same time

Obesity is considered one of the important risk factors for this disease, possibly through systemic inflammation (216)