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The RMSD plot analysis of fusion proteins complexed with GLP-1 receptor during 200 ns of the MD simulation showed that all three docked complexes stabilized after 50 ns and remained stable throughout the rest of the simulation time with RMSD values of 0.8 0.08, 0.9 0.09, and 0.81 0.1 for nGLP1-DARPin, mGLP1-DARPin-1, and mGLP1-DARPin-2 complex with GLP-1R, respectively (Fig

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[DOI] [PubMed] [Google Scholar] 120.Eckstein N, et al