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Institute of Medicine, National Academies Press, Washington Iovine B, Guardia F, Irace C et al (2016) L-carnosine dipeptide overcomes acquired resistance to 5-fluorouracil in HT29 human colon cancer cells via downregulation of HIF1-alpha and induction of apoptosis

DISCUSSION By combining previous models and making a few parameter changes, we have created a new model of glutathione metabolism that we have used to investigate sexual dimorphism in the glutathione pathway in the liver