While the first GLP-1 medication was approved by the FDA in 2005, this class of medications has drawn new attention in the past few years as more medications have gained approval
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Par Health L00H97 Rev 01/2026 Multiple strengths
Regulatory Status and Legal Considerations Regulatory status varies globally
Insurers needed solutions that worked within the fiscal year, not across decades
The standard dosing schedule starts at 2.5 mg weekly and escalates every four weeks: Weeks 14: 2.5 mg weekly (initiation dose to acclimate to GLP-1/GIP receptor activation) Weeks 58: 5 mg weekly Weeks 912: 7.5 mg weekly (optional intermediate step) Weeks 1316: 10 mg weekly Weeks 1720: 12.5 mg weekly (optional intermediate step) Week 21 onward: 15 mg weekly (maximum maintenance dose) Tirzepatide is injected subcutaneously just under the skin using a pre-filled pen or syringe
