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A blood test is helpful but not always required

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Meldrum et al., lower levels of both cellular and circulating antioxidants in men with ED are most likely due to oxidative stress and/or low antioxidant intake

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But when oxidative stress is high (excess reactive oxygen species), it can be used up more quickly.[ref] Studies show that Vitamin C increases nitric oxide through increasing BH4 bioavailability.[ref] Curcumin for NOS3