It appeared that the muscle loss was less than fat
Vilarrasa E, Nicolau J, de la Cueva P, Goday A, Gallardo F, Martorell A, et al
Preliminary data from a phase 1b extension study (NCT05292911) involving 64 individuals with MRI-PDFF 10% and BMI 28 kg/m 2 demonstrated that 50%, 44%, and 60% of participants presenting baseline alanine aminotransferase (ALT) 30 IU/L reached combined MRI-PDFF reduction 30% and ALT reduction 17 IU/L at pemvidutide doses of 1.2, 1.8, and 2.4 mg, respectively, vs
Pain Freedom: More than 1 in 8 patients reported complete freedom from knee pain by the end of the trial
Hormonal Changes Weight loss can lead to alterations in hormones like testosterone and growth hormone , which play a role in muscle maintenance
Attempting to add tirzepatide on top of it is like trying to add more engine to a car that's already been precision-engineered for maximum performance