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The safety profile, optimal dosing strategies, and long-term effects in humans have not been fully established

As indicated, the major regulator of eNOS (and nNOS) activity is Ca 2+ ion

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High levels of ROS, excessive inflammatory cells and cytokines in the wound microenvironment, insufficient new blood vessels, and weakened cell proliferation are the key factors that lead to the difficult healing of diabetic wounds 24

Glutathione is also called as then master antioxidant due to its central role in cellular defense

Tocopherol (Vitamin E): An antioxidant that protects the scalp from free radical damage and improves overall scalp health