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Reports on Phase I clinical trials showed minor drug-related side effects that included fatigue, nausea, vomiting, and hematuria with no indications of cumulative toxicity

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Our study identified HAE type I in five unrelated families with 10 individuals in the Federation of Bosnia and Herzegovina

Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis

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