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Optimization of operational parameters such as temperature, solvent composition, solvent-to-feed ratio, and extraction time is essential but can be complex and sample-specific, especially when dealing with complex matrices like propolis (77)

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Interestingly, both LQ and LQG could significantly up regulate tyrosinase activity and the expression of MITF and its downstream TRP-1 and Trp-2

Beyond the normal noise of daily weight fluctuation, there are several physiological and behavioural reasons why a calorie deficit may appear to stall, even over a longer period

Treatment efficacy varies from person to person, and maintaining treatment results often requires ongoing use of these therapies