29 GLP-1, an endocrine hormone, is secreted by enteroendocrine L-cells located in the distal jejunum, ileum, and colon in response to nutrient ingestion and neuroendocrine stimulation
Looking forward, the horizon seems promising for GLP-1 agonists, with new formulations and combination therapies under investigation
Heres what to keep an eye on: Body Weight and Rate of Loss Stick to weekly weigh-ins not daily ones
When food enters the digestive system, GLP-1 is released and acts on multiple targets: it stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways
These include feeling nauseated, vomiting, diarrhea, upset stomach, headache, dizziness and a complete loss of appetite
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