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A true 'washout' from Melanotan-2 requires 48 weeks for natural skin cell turnover to remove visible pigmentation entirely

Endocr Rev (2013) 34:30938

Repeated missed doses, however, will prevent steady state maintenance and reduce efficacy

However, as a branded medication, its availability is often subject to supply chain issues, which has led many individuals to seek alternative ways to access the same active ingredient

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