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Each year, RA has a devastating financial impact of $50 billion in lost productivity and health care costs [1]

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[2] Newsome PN, Buchholtz K, Cusi K, Linder M, Okanoue T, Ratziu V, Sanyal AJ, Sejling AS, Harrison SA

When evaluating adipose tissue in WT and 3-KO mice, researchers found that neither treatment significantly affected white adipose tissue mass in either genotype

doi: 10.3390/ijms21010155 101 LiuSHartlebenBKretzOWiechTIgarashiPMizushimaNet al

10.1016/j.ccr.2010.12.014 314 YanagisawaN.IchinoeM.MikamiT.NakadaN.HanaK.KoizumiW.et al