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Gut dysbiosis may influence the progression of PCOS through various mechanisms

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The overall result is a progressive deficiency that worsens as the condition develops

Coherus said the observationcommunicated in an FDA Form 483is readily addressable and the company continues to anticipate potential approval for toripalimab by year end 2023. Coherus and its partner Junshi Biosciences received a CRL for toripalimab in this indication requesting a quality process change in May 2022

Reported symptoms include chest pain, shortness of breath, rapid heart rate, calf pain, and sudden worsening of breathing