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It helps the body to detoxify fats before bile is released, reducing the digestive load on the gallbladder

Johnson DA, Oldfield EC

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A typical research loading protocol might involve daily administration of a dose ranging from 250mcg to 1mg

Individuals with a deficiency in vitamin B12 may experience symptoms such as fatigue, weakness, and changes in weight or metabolism

In addition, deletion of the GSH1 geneencoding glutamylcysteine synthetase (GCS), the enzyme catalysing the first step in glutathione synthesiswas shown to suppress an Ero1 conditional mutant, again indicating that GSH provides an additional load on Ero1 activity (Frand & Kaiser, 1998)