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These results highlight the importance of further exploring the mechanisms underlying organ-specific aging, informed by established hallmarks of aging, which could pave the way for effective interventions aimed at enhancing healthspan and mitigating negative health outcomes related to aging

We used our model to test the importance of glucoronidation and its sensitivity to the activity of the glucoronosyl tranferase enzymes by computing the amount of liver damage resulting from a moderate overdose (10 g) with different choices for the V max values of the glucoronosyl tranferases

Placental exosomes can be detected in maternal blood as early as 6 weeks after conception and gradually increase until peaking at term (85)