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Stabilization of the transition state in each reaction step may be provided by a conserved arginine that facilitates peptide bond formation

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First, optimal patient selection criteria remain poorly defined

TGF-1 could also induce adult mouse hepatocytes to undergo EMT, and up to 45% of the FSP1-postive fibroblasts are derived from hepatocytes in carbon tetrachloride (CCL4)-induced fibrotic liver (94)