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Exendin-(939) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3, 5-monophosphate levels and -cell glucose competence
Immediately after being secreted, GLP-1 enters the capillaries and is rapidly degraded by dipeptidyl peptidase-4 (DPP-4)
Consistently, increased levels of GLP-1 and insulin could be observed in MMI + T3-5d mice compared to MMI mice even without oral glucose load (Fig
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