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It is metabolized into several peptide fragments, primarily involving proline-rich sequences, and eliminated with a half-life under 30 minutes

Some methods useful in other locations, such as cryotherapy or ablative lasers, are discouraged in the periungual region due to the risk of permanent matrix damage

J Biol Chem 269(37):2317123176 Lundberg M, Johansson C, Chandra J, Enoksson M, Jacobsson G, Ljung J, Johansson M, Holmgren A Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms

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This was followed by a 6-week washout period