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GSH, released by astrocytes, undergoes a cleavage process by -glutamyl transpeptidase (GT) [29] producing a -glutamyl moiety and a dipeptide CysGly which is an essential precursor of neuronal glutathione

Many cancers like prostate cancer and cancers of the spinal cord itself result in the narrowing of the passageways in the vertebral column and cause spinal cord or nerve root compression

Steady-state GPX4/GSH system The integrity of the GPX4/GSH antioxidant axis is critical for dopaminergic neuron survival

It helps detoxify heavy metals and environmental toxins

Increasing growth hormone and IGF-1 levels may carry potential risks, including worsening insulin resistance in some individuals and, theoretically, stimulating the growth of existing cancers

Acute overdose is unlikely to cause serious harm rodent LD50 data suggest a wide safety margin but doubling dose wont double cognitive benefits due to receptor saturation