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In more stubborn conditions, it can last 8 to 12 weeks, followed by a break

10.1006/jmbi.1996.0018 651 UverskyV

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Potential Side Effects of Vitamin B-Complex: What You Should Know While Vitamin B-Complex is generally nontoxic and necessary for maintaining health, hypersensitivity to some B vitamins or overuse can cause negative consequences

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doi: 10.1002/hep.510300622