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Evidence that SODs defend against oxidative stress has been obtained using transgenic mutants that either overexpress or lack these antioxidant enzymes [111]

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High-dose oral cyanocobalamin (1,000 mcg daily) is effective for many patients after sleeve gastrectomy, as a small proportion is absorbed passively without intrinsic factor

As more patients arrive having researched therapies with AI, physicians will need to spend as much time discussing the quality of the evidence as the proposed mechanism.