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Alcohol binge-induced cardiovascular dysfunction involves endocannabinoid-CB1-R signaling

Statistical analysis Statistical analysis was performed by parametric one-way analysis of variance, with post-hoc Newman-Keuls test and non-parametric Kruskal-Wallis test and subsequently the Mann-Whitney U test to compare groups

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NF-B is activated through cytokines (such as TNF- and IL-1), oxidative stress, pathogen-associated molecular patterns (PAMPs), and DNA damage, which stimulate the IB kinase (IKK) complex to phosphorylate IB inhibitors