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10.1016/j.celrep.2017.04.004 31 LvL.ChenZ.BaiW.HaoJ.HengZ.MengC.et al (2023)

For hair : Subcutaneous injection (systemic) combined with scalp microneedling and topical application delivers optimal follicular penetration

This is why patients with neurological involvement are often maintained on a more frequent schedule (every 2 months rather than every 3 months)

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In the cyanocobalamin plus glutathione mono-anion model, the HOMO orbital- usually seen in ground state calculations- shows an intermolecular character where the main contribution comes from the monoanion s electronic structure, with additional input from cyanocobalamin