Regular follow-up should include assessment of weight loss trajectory, tolerability, medication adherence, and renal function if significant GI symptoms occur
The lack of appetite effects means there is no rebound hunger concern when discontinuing, and the absence of hormonal suppression means no post-cycle therapy is required
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In a 2018 review, researchers found evidence that taking 1,000 mcg of B12 and getting B12 injections had similar effects on treating B12 deficiencies
Week 1-2: Minimal visible changes You're unlikely to see much in the first two weeks