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Nat Med 19 , 576585 (2013)

doi:10.1016/j.ympev.2012.07.011

They ease off over several weeks as blood levels fall

Together, these changes reduce cardiometabolic risk and may improve overall quality of life by addressing multiple health factors at once

Warnings: If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use

The mechanism involves the conversion of acetaminophen to p-aminophenol, which crosses the blood-brain barrier and is metabolized by FAAH to yield AM404