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These symptoms typically occur during the early stages of treatment as the body adjusts to the medication

Mechanisms and clinical efficacy of lixisenatide for the management of type 2 diabetes

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or persistent and 1 mgpatients persistent to the index therapy and receiving maximum dose 1 mg over the follow-up period

Although glucose profiles did not change significantly, insulin and C-peptide concentrations were reduced significantly after intervention (P-values 0.043 for insulin and 0.006 for C-peptide), particularly during intermediate time points (30 to 150 minutes