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No direct anti-inflammatory mechanism for retatrutide has been confirmed in clinical trials

Wang G, Kong B, Shuai W, Fu H, Jiang X et al (2020) 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice

When cells are exposed to OS, BACH1 becomes inactivated, which allows NRF2 to bind to the ARE and induce the expression of protective antioxidant genes [222]

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